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U.S. Biotechnology Stocks

606 companies by market cap.

As of Nov 6, 2026

There are 606 U.S.-listed companies in Biotechnology (Healthcare sector), with a combined market value of $1.32T. The largest is Vertex Pharmaceuticals Incorporated at 11% of the total. The median P/E is 14.8x, the median revenue growth is +8.5%, and 4 companies pay a dividend.

#CompanyMarket capP/EDiv. yieldRevenue YoY1Y return
1Vertex Pharmaceuticals IncorporatedVRTXVertex Pharmaceuticals Incorporated is a leading biotechnology firm primarily focused on the discovery, advancement, and marketing of innova…$139B31.6x—+10.6%+31.4%
2Moderna, Inc.MRNAModerna, Inc., a biotechnology firm, is dedicated to the discovery, development, and commercialization of messenger RNA (mRNA) based therapi…$101B——−27.2%+944.8%
3Regeneron Pharmaceuticals, Inc.REGNRegeneron Pharmaceuticals, Inc.$93.5B21.7x0.41%+9.3%+40.5%
4argenx SEARGXargenx SE, a biotechnology company established in Amsterdam, the Netherlands, in 2008, is dedicated to developing innovative therapies prima…$55.3B31.9x——+9.0%
5BeOne Medicines AGONCBeOne Medicines AG, an oncology company, engages in discovering and developing various treatments for cancer patients in the United States,…$43.5B27.0x—+34.3%+22.4%
6Revolution Medicines, Inc.RVMDRevolution Medicines, Inc.$41.2B———+213.3%
7Genmab A/SGMABGenmab A/S, a biopharmaceutical company founded in 1999 and headquartered in Copenhagen, Denmark, specializes in the discovery and developme…$33B41.7x—−68.2%+86.0%
8Roivant Sciences Ltd.ROIVRoivant Sciences Ltd.$28.1B——−67.6%+89.0%
9Insmed IncorporatedINSMInsmed Incorporated operates as a biopharmaceutical enterprise focused on creating and introducing medical solutions for individuals facing…$25.1B——+185.8%−38.4%
10Incyte CorporationINCYIncyte Corporation is a biopharmaceutical firm engaged in the research, development, and global marketing of its own innovative therapies.$24.4B14.8x—+26.9%+13.7%
11United Therapeutics CorporationUTHRUnited Therapeutics Corporation, a biotechnology firm, is dedicated to discovering, developing, and bringing to market medical solutions for…$24.1B18.6x—+2.5%+23.8%
12BioNTech SEBNTXBioNTech SE, a biotechnology firm, specializes in the creation and marketing of immune-based treatments for malignancies and various infecti…$21.7B——−8.2%−15.3%
13Alnylam Pharmaceuticals, Inc.ALNYAlnylam Pharmaceuticals, Inc.$20.9B25.6x—+95.1%−64.6%
14Exelixis, Inc.EXELExelixis, Inc.$17.5B21.1x—+9.2%+70.5%
15Ascendis Pharma A/SASNDAscendis Pharma A/S is a biopharmaceutical enterprise dedicated to advancing therapeutic solutions for critical medical conditions that curr…$16.9B20.0x—+114.9%+28.9%
16Neurocrine Biosciences, Inc.NBIXNeurocrine Biosciences, Inc.$16.7B23.2x—+34.4%+6.4%
17Jazz Pharmaceuticals plcJAZZJazz Pharmaceuticals plc identifies, develops, and commercializes pharmaceutical products in the United States, Europe, and internationally.$15.1B15.3x—+12.6%+75.1%
18BridgeBio Pharma, Inc.BBIOBridgeBio Pharma, Inc.$14.5B——+202.4%+18.4%
19Summit Therapeutics Inc.SMMTSummit Therapeutics Inc.$13B———−11.5%
20Halozyme Therapeutics, Inc.HALOHalozyme Therapeutics, Inc.$11.8B29.4x—+41.2%+51.5%
21Bio-Techne CorporationTECHBio-Techne Corporation, together with its subsidiaries, develops, manufactures, and sells life science reagents, instruments, and services f…$11.4B62.3x0.44%−0.4%+25.8%
22Kymera Therapeutics, Inc.KYMRKymera Therapeutics, Inc.$11.2B——+134.8%+116.0%
23BioMarin Pharmaceutical Inc.BMRNBioMarin Pharmaceutical Inc.$10.8B147.4x—+11.2%+8.1%
24Vaxcyte, Inc.PCVXVaxcyte, Inc.$10.1B———+53.2%
25Spyre Therapeutics, Inc.SYRESpyre Therapeutics, Inc.$9.6B———+363.9%
26Madrigal Pharmaceuticals, Inc.MDGLMadrigal Pharmaceuticals, Inc.$9.2B——+149.0%−18.2%
27TG Therapeutics, Inc.TGTXBased in New York City and established in 1993, TG Therapeutics, Inc.$9.2B19.6x—+76.1%+79.9%
28ImmunityBio, Inc.IBRXImmunityBio, Inc.$9.2B——+192.9%+307.3%
29Krystal Biotech, Inc.KRYSKrystal Biotech, Inc.$8.9B36.5x—+22.6%+50.5%
30Protagonist Therapeutics, Inc.PTGXProtagonist Therapeutics, Inc.$8.5B108.4x—+34.8%+65.5%
31Arrowhead Pharmaceuticals, Inc.ARWRArrowhead Pharmaceuticals, Inc., founded in 1989 and based in Pasadena, California, is a biopharmaceutical company dedicated to discovering…$8.2B——+16.8%+46.9%
32Twist Bioscience CorporationTWSTTwist Bioscience Corporation operates as a leading synthetic biology firm, specializing in the production and sale of products developed fro…$8B——+19.2%+294.4%
33Praxis Precision Medicines, Inc.PRAXPraxis Precision Medicines, Inc.$7.8B———+61.1%
34Rhythm Pharmaceuticals, Inc.RYTMRhythm Pharmaceuticals, Inc.$7.7B——+53.5%+14.0%
35Abivax S.A.ABVXAbivax S.A., operating as ABIVAX Société Anonyme, is a French pharmaceutical firm focused on the discovery and optimization of therapeutic d…$7.5B———−17.5%
36Cytokinetics, IncorporatedCYTKCytokinetics, Incorporated, a biopharmaceutical company, focuses on discovering, developing, and commercializing novel muscle activators and…$7.5B——−17.2%−11.0%
37Caris Life Sciences, Inc.CAICaris Life Sciences, Inc.$7.1B67.8x—+85.4%+2.5%
3810x Genomics, Inc.TXGHeadquartered in Pleasanton, California, 10x Genomics, Inc.$7.1B——−4.3%+356.0%
39Axsome Therapeutics, Inc.AXSMAxsome Therapeutics, Inc.$7B——+56.9%−5.0%
40Oruka Therapeutics, Inc.ORKAOruka Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing novel monoclonal antibody therapeutics for psori…$6.8B———+263.7%
41CG Oncology Inc.CGONCG Oncology, Inc., a late-stage clinical biopharmaceutical company, develops and commercializes cretostimogene grenadenorepvec for patients…$6.7B——+1,030.3%+91.5%
42Ionis Pharmaceuticals, Inc.IONSFounded in 1989 and headquartered in Carlsbad, California, Ionis Pharmaceuticals, Inc.$6.6B——−7.4%−46.8%
43Immunovant, Inc.IMVTImmunovant, Inc.$6.3B———+29.0%
44Kodiak Sciences Inc.KODKodiak Sciences Inc.$6.2B———+487.6%
45Belite Bio, IncBLTEBelite Bio, Inc.$6.1B———+38.0%
46Ligand Pharmaceuticals IncorporatedLGNDLigand Pharmaceuticals Incorporated operates as a biopharmaceutical entity, primarily engaged in sourcing and advancing technologies to empo…$6.1B30.7x—+54.9%+47.1%
47Mirum Pharmaceuticals, Inc.MIRMMirum Pharmaceuticals, Inc.$6.1B——+44.0%+38.4%
48Veradermics, IncorporatedMANEVeradermics, Incorporated functions as a biopharmaceutical enterprise focused on devising pioneering therapeutic interventions for various s…$5.8B———+202.1%
49Scholar Rock Holding CorporationSRRKScholar Rock Holding Corporation is a biopharmaceutical firm dedicated to discovering and advancing treatments for severe medical conditions…$5.7B———+63.0%
50Cogent Biosciences, Inc.COGTCogent Biosciences, Inc.$5.5B———+115.0%
51PTC Therapeutics, Inc.PTCTPTC Therapeutics, Inc.$5.5B——−42.8%−9.8%
52Erasca, Inc.ERASErasca, Inc.$5B———+543.3%
53CRISPR Therapeutics AGCRSPCRISPR Therapeutics AG (CRSP) is a biotechnology firm dedicated to pioneering gene-based medicines for severe diseases.$4.9B——−64.2%−11.5%
54Edgewise Therapeutics, Inc.EWTXEdgewise Therapeutics, Inc.$4.8B———+163.6%
55Dianthus Therapeutics, Inc.DNTHDianthus Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of therapies for patients with severe autoim…$4.8B——−60.8%+136.2%
56Travere Therapeutics, Inc.TVTXTravere Therapeutics, Inc.$4.8B——+77.1%+49.0%
57Definium Therapeutics, Inc.DFTXDefinium Therapeutics, Inc.$4.5B———+193.4%
58Adaptive Biotechnologies CorporationADPTAdaptive Biotechnologies Corporation, founded in 2009 and headquartered in Seattle, Washington (operating as Adaptive TCR Corporation until…$4.5B——+50.1%+79.8%
59Legend Biotech CorporationLEGNLegend Biotech Corporation, through its subsidiaries, operates as a biopharmaceutical company that discovers, develops, manufactures, and co…$4.3B——+59.5%−27.7%
60Relay Therapeutics, Inc.RLAYRelay Therapeutics, Inc.$4.1B——+23.9%+184.9%
61AbCellera Biologics Inc.ABCLAbCellera Biologics Inc.$3.8B——+101.3%+162.3%
62Xenon Pharmaceuticals Inc.XENEXenon Pharmaceuticals Inc.$3.8B———+2.3%
63Amylyx Pharmaceuticals, Inc.AMLXAmylyx Pharmaceuticals, Inc.$3.7B———+136.7%
64Acadia Pharmaceuticals Inc.ACADAcadia Pharmaceuticals Inc.$3.7B9.4x—+11.8%−1.9%
65Iovance Biotherapeutics, Inc.IOVAIovance Biotherapeutics, Inc., a biotechnology firm currently in the clinical development stage, is committed to discovering and bringing to…$3.6B——+34.5%+248.0%
66Tango Therapeutics, Inc.TNGXTango Therapeutics, Inc.$3.6B——+121.5%+168.4%
67Enliven Therapeutics, Inc.ELVNEnliven Therapeutics, Inc.$3.6B———+170.1%
68Parabilis Medicines, Inc.PBLSFog Pharmaceuticals, Inc.$3.5B———+25.2%
69Viking Therapeutics, Inc.VKTXViking Therapeutics, Inc.$3.4B———−28.0%
70Tarsus Pharmaceuticals, Inc.TARSTarsus Pharmaceuticals, Inc.$3.4B——+105.2%+0.7%
71Dyne Therapeutics, Inc.DYNDyne Therapeutics, Inc.$3.4B———−0.7%
72Telix Pharmaceuticals LimitedTLXTelix Pharmaceuticals Limited, a commercial-stage biopharmaceutical company, focuses on the development and commercialization of therapeutic…$3.3B99.8x—+202.0%−2.5%
73Celcuity Inc.CELCCelcuity, Inc.$3.3B———−10.0%
74Viridian Therapeutics, Inc.VRDNViridian Therapeutics, Inc.$3.2B——+23,220.3%+3.6%
75Arcutis Biotherapeutics, Inc.ARQTArcutis Biotherapeutics, Inc.$3.2B115.7x—+76.1%+1.8%
76Denali Therapeutics Inc.DNLIDenali Therapeutics Inc.$3.2B———+39.3%
77Disc Medicine, Inc.IRONBased in Watertown, Massachusetts, Disc Medicine, Inc.$3B———−9.3%
78IDEAYA Biosciences, Inc.IDYAIDEAYA Biosciences, Inc.$3B——+3,244.7%+4.7%
79Zai Lab LimitedZLABOperating primarily in Mainland China and Hong Kong, Zai Lab Limited is a biopharmaceutical company focused on the discovery, development, a…$2.9B——+5.1%+10.1%
80ADMA Biologics, Inc.ADMAADMA Biologics, Inc.$2.9B17.7x—+8.0%−9.3%
81Vericel CorporationVCELVericel Corporation operates as a biopharmaceutical firm that has reached the commercialization phase, specializing in the research, develop…$2.8B113.8x—+23.0%+41.0%
82Xeris Biopharma Holdings, Inc.XERSXeris Biopharma Holdings, Inc.$2.8B——+36.3%+97.2%
83Beam Therapeutics Inc.BEAMBeam Therapeutics Inc., founded in 2017 and based in Cambridge, Massachusetts, operates as a pioneering biopharmaceutical firm.$2.7B——+158.9%+14.1%
84Xencor, Inc.XNCRXencor Inc., a biopharmaceutical firm headquartered in Monrovia, California, and established in 1997, operates as a clinical-stage entity.$2.7B——−36.1%+155.4%
85Palvella Therapeutics, Inc.PVLAPalvella Therapeutics, Inc.$2.5B———+123.7%
86MBX Biosciences, Inc. Common StockMBXMBX Biosciences, Inc.$2.5B———+107.6%
87Pharvaris N.V.PHVSPharvaris N.V., a late-stage biopharmaceutical company, focuses on the development and commercialization of therapies for rare diseases with…$2.4B———+57.8%
88Celldex Therapeutics, Inc.CLDXCelldex Therapeutics, Inc.$2.3B——−98.1%+28.4%
89Arcus Biosciences, Inc.RCUSArcus Biosciences, Inc., a clinical-stage biopharmaceutical company, develops and commercializes cancer therapies in the United States.$2.3B——−55.3%−6.5%
90Hemab Therapeutics Holdings, Inc. Common StockCOAGHemab Therapeutics Holdings, Inc.$2.3B———−4.4%
91Septerna IncSEPNSepterna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule product…$2.3B——+13,520.1%+159.8%
92NewAmsterdam Pharma Company N.V.NAMSNewAmsterdam Pharma Company N.V., a late-stage biopharmaceutical company, develops therapies to enhance patient care in populations with car…$2.3B——−88.9%−49.0%
93Immunome, Inc.IMNMImmunome, Inc., a biotechnology company, engages in the discovery, design, development, manufacturing, and commercialization of antibody-dru…$2.2B———+20.7%
94Aurinia Pharmaceuticals Inc.AUPHAurinia Pharmaceuticals Inc.$2.2B7.0x—+19.8%+18.0%
95Recursion Pharmaceuticals, Inc.RXRXRecursion Pharmaceuticals, Inc.$2.2B——−14.9%−23.9%
96Lakefront Biotherapeutics N.V.LKFTLakefront Biotherapeutics NV, formerly Galapagos NV, is a biotechnology company that focuses on transforming patient outcomes through scient…$2.2B4.1x—+259.4%+7.2%
97Biohaven Ltd.BHVNBiohaven Ltd., a biopharmaceutical company, focuses on the discovery, development, and commercialization of treatments for immunology, neuro…$2.2B———+69.8%
98Vera Therapeutics, Inc.VERAVera Therapeutics, Inc.$2.1B———+18.1%
99Maravai LifeSciences Holdings, Inc.MRVIMaravai LifeSciences Holdings, Inc.$2.1B——−3.3%+160.4%
100Zymeworks Inc.ZYMEZymeworks Inc.$2.1B——−69.8%+65.5%
101Fortrea Holdings Inc.FTREFortrea Holdings Inc.$2.1B——−2.1%+99.3%
102Vir Biotechnology, Inc.VIRVir Biotechnology, Inc.$2.1B——+1,495.9%+138.4%
103Replimune Group, Inc.REPLReplimune Group, Inc.$2B———+154.4%
104Trevi Therapeutics, Inc.TRVITrevi Therapeutics, Inc.$2B———+30.2%
105First Tracks Biotherapeutics IncTRAXFirst Tracks Biotherapeutics, Inc., situated in San Diego, California, specializes in pioneering new immunology-based treatments.$2B———+89.7%
106BioCryst Pharmaceuticals, Inc.BCRXBioCryst Pharmaceuticals, Inc.$2B——+68.7%+9.3%
107Alamar Biosciences, Inc.ALMRAlamar Biosciences operates as a commercial-stage proteomics firm, specializing in the highly sensitive, simultaneous identification of vari…$1.9B———+25.9%
108Harmony Biosciences Holdings, Inc.HRMYHarmony Biosciences Holdings, Inc.$1.9B10.6x—+24.3%+7.0%
109Maze Therapeutics, Inc.MAZEMaze Therapeutics, Inc., a clinical stage biopharmaceutical company, develops small molecule precision medicines for the treatment of kidney…$1.9B——+700.0%+15.4%
110Sarepta Therapeutics, Inc.SRPTSarepta Therapeutics, Inc.$1.9B——−20.4%+1.0%
111Mesoblast LimitedMESOMesoblast Limited is a biopharmaceutical firm dedicated to the development and commercialization of allogeneic cell-based therapies.$1.9B——+602.3%−4.4%
112Zenas BioPharma, Inc.ZBIOZenas BioPharma, Inc.$1.8B——−93.3%−12.9%
113Novavax, Inc.NVAXNovavax, Inc.$1.8B——−61.6%+42.0%
114Agios Pharmaceuticals, Inc.AGIOAgios Pharmaceuticals, Inc.$1.8B——+140.6%−27.0%
115Absci CorporationABSIAbsci Corporation operates as a biopharmaceutical company primarily focused on discovering novel drug targets and developing new therapeutic…$1.7B——−62.3%+183.3%
116Stoke Therapeutics, Inc.STOKStoke Therapeutics, Inc.$1.7B——−86.2%+18.1%
117SELLAS Life Sciences Group, Inc.SLSSELLAS Life Sciences Group, Inc., a late-stage clinical biopharmaceutical company, focuses on the development of novel therapeutics for vari…$1.7B———+419.8%
118Kailera Therapeutics, Inc.KLRAKailera Therapeutics, Inc.$1.7B———−55.0%
119Generate Biomedicines, Inc.GENBGenerate Biomedicines, Inc.$1.7B———+3.2%
120Nurix Therapeutics, Inc.NRIXNurix Therapeutics, Inc., a clinical stage biopharmaceutical company, focuses on the discovery, development, and commercialization of small…$1.7B6.4x—+738.8%+22.2%
121Precigen, Inc.PGENPrecigen, Inc.$1.6B——+1,875.0%+14.0%
122Immunocore Holdings plcIMCRImmunocore Holdings plc, a biotechnology firm established in 1999 and based in Abingdon, United Kingdom, has reached the commercial stage in…$1.6B——+13.4%−1.9%
123Intellia Therapeutics, Inc.NTLAIntellia Therapeutics, Inc.$1.6B——+12.6%−7.9%
124Nanobiotix S.A.NBTXNanobiotix S.A.$1.6B——−61.8%+55.7%
125Ultragenyx Pharmaceutical Inc.RAREUltragenyx Pharmaceutical Inc.$1.5B——+17.5%−50.1%
126uniQure N.V.QUREuniQure N.V.$1.5B——+30.2%−21.1%
127ADARx Pharmaceuticals, Inc.ADRXADARx Pharmaceuticals, Inc.$1.5B———−7.3%
128Damora Therapeutics, Inc.DMRADamora Therapeutics, Inc., a biopharmaceutical company, develops therapies for the treatment of hematologic disorders in Denmark and North A…$1.5B———+307.2%
129Nuvation Bio Inc.NUVBNuvation Bio Inc.$1.5B——+1,083.6%−17.0%
130Ocular Therapeutix, Inc.OCULOcular Therapeutix, Inc.$1.4B——−8.1%−37.9%
131Ascentage Pharma Group InternationalAAPGBased in Suzhou, China, Ascentage Pharma Group International is a biotechnology firm primarily focused on clinical-stage development.$1.4B——−11.0%−52.3%
132Taysha Gene Therapies, Inc.TSHATaysha Gene Therapies, Inc.$1.4B——−32.3%+10.5%
133AnaptysBio, Inc.ANABAnaptysBio, Inc., a clinical-stage biotechnology company, focuses in delivering immunology therapeutics for autoimmune and inflammatory dise…$1.4B6.9x—+92.9%+82.4%
134Kardigan, Inc.KARDKardigan, Inc.$1.4B———−36.9%
135Innoviva, Inc.INVAInnoviva, Inc.$1.4B3.9x—+19.8%−7.2%
136Mineralys Therapeutics, Inc.MLYSMineralys Therapeutics, Inc.$1.4B———−58.6%
137LB Pharmaceuticals Inc Common StockLBRXThis biopharmaceutical firm is currently in the clinical development stage, concentrating on the creation of innovative treatments for neuro…$1.4B———+170.9%
138Braveheart Bio, Inc.BRVEBraveheart Bio, Inc.$1.3B———−34.4%
139Avalyn Pharma Inc. Common StockAVLNAvalyn Pharma Inc.$1.3B———−16.4%
140GH Research PLCGHRSGH Research PLC is a clinical-stage biopharmaceutical firm dedicated to creating novel therapies for psychiatric and neurological conditions…$1.3B———+38.8%
141Alpha Tau Medical LtdDRTSAlpha Tau Medical Ltd., a clinical-stage oncology therapeutics company, focuses on the research, development, and commercialization of diffu…$1.3B———+261.1%
142Tyra Biosciences, Inc.TYRATyra Biosciences, Inc.$1.3B———+48.1%
143MannKind CorporationMNKDMannKind Corporation operates as a biopharmaceutical firm, primarily focused on innovating and bringing to market respiratory-delivered trea…$1.3B——+30.5%−31.6%
144Inhibrx Biosciences Inc.INBXInhibrx Biosciences, Inc.$1.2B———+4.4%
145SpyGlass Pharma, Inc. Common StockSGPSpyGlass Pharma, Inc.$1.2B———−6.4%
146Omeros CorporationOMEROmeros Corporation is a biopharmaceutical firm with commercialized products, actively engaged in the discovery, development, and market intr…$1.2B8.9x——+157.1%
147COMPASS Pathways plcCMPSCOMPASS Pathways plc is a mental healthcare company with a primary presence in the United Kingdom and the United States.$1.2B———+54.0%
148UroGen Pharma Ltd.URGNUroGen Pharma Ltd., a biotechnology company, engages in the development and commercialization of solutions for urothelial and specialty canc…$1.2B——+100.3%+5.2%
149Rapport Therapeutics, Inc. Common StockRAPPRapport Therapeutics, Inc.$1.2B———−3.6%
150Structure Therapeutics Inc.GPCRStructure Therapeutics Inc., an international biopharmaceutical company currently in its clinical development phase, is committed to creatin…$1.2B———−39.2%
151Seaport Therapeutics, Inc. Common StockSPTXSeaport Therapeutics, Inc.$1.2B———−11.3%
152Janux Therapeutics, Inc.JANXJanux Therapeutics, Inc.$1.1B——+5,367.0%−38.5%
153Vor Biopharma Inc.VORVor Biopharma, Inc.$1.1B———+4.8%
154Nektar TherapeuticsNKTRNektar Therapeutics is a biopharmaceutical firm dedicated to the global discovery and advancement of therapies addressing significant unmet…$1.1B——−27.2%−32.4%
155Savara Inc.SVRASavara Inc.$992M———+21.4%
156Alto Neuroscience, Inc.ANROAlto Neuroscience, Inc.$987M———+126.1%
157MoonLake ImmunotherapeuticsMLTXMoonLake Immunotherapeutics operates as a clinical-stage biopharmaceutical company, concentrating its efforts on discovering and developing…$981M———+12.1%
158Jade Biosciences, Inc.JBIOJade Biosciences, Inc.$958M———+68.4%
159Immatics N.V.IMTXImmatics N.V.$952M——−68.0%−31.1%
160Silence Therapeutics plcSLNSilence Therapeutics plc is a London, UK-based biotechnology company specializing in the research and development of groundbreaking ribonucl…$932M——−97.6%+205.9%
161Odyssey Therapeutics, Inc.ODTXOdyssey Therapeutics, Inc.$924M———+7.0%
162ORIC Pharmaceuticals, Inc.ORICORIC Pharmaceuticals, Inc.$914M———−29.7%
163Monte Rosa Therapeutics, Inc.GLUEMonte Rosa Therapeutics, Inc.$902M——−83.9%−18.8%
164Corvus Pharmaceuticals, Inc.CRVSCorvus Pharmaceuticals, Inc.$887M———+34.8%
165Pharming Group N.V.PHARPharming Group N.V.$870M84.0x—−99.6%−16.4%
166MeiraGTx Holdings plcMGTXMeiraGTx Holdings plc operates as a clinical-stage gene therapy company, dedicated to pioneering therapeutic solutions for individuals affli…$864M11.8x—+948.3%+7.0%
167Syndax Pharmaceuticals, Inc.SNDXSyndax Pharmaceuticals, Inc.$859M——+222.3%−35.1%
168Aktis Oncology, Inc.AKTSAktis Oncology, Inc.$850M———−28.5%
169Prime Medicine, Inc.PRMEPrime Medicine, Inc.$843M——−17.9%+11.2%
170Lexicon Pharmaceuticals, Inc.LXRXLexicon Pharmaceuticals, Inc.$792M——−29.0%+24.5%
171Alumis Inc.ALMSAlumis Inc., a clinical stage biopharmaceutical company, focuses on the development and commercialization of medicines for autoimmune disord…$780M——−63.1%+27.8%
172Verastem, Inc.VSTMVerastem, Inc.$762M——+3,995.7%+6.1%
173Ginkgo Bioworks Holdings, Inc.DNAGinkgo Bioworks Holdings, Inc., together with its subsidiaries, develops a platform for cell engineering in the United States.$760M——−51.5%−0.1%
174Rigel Pharmaceuticals, Inc.RIGLRigel Pharmaceuticals, Inc., a biotechnology company, develops and provides therapies that enhance the lives of patients with hematologic di…$741M2.2x—+3.3%+9.8%
175OmniAb, Inc.OABIOmniAb, Inc.$734M——+66.9%+264.5%
176Arbutus Biopharma CorpABUSArbutus Biopharma Corporation, a clinical-stage biopharmaceutical company, develops novel therapeutics for infectious disease in the United…$724M4.6x—+1,078.8%−17.7%
177Ardelyx, Inc.ARDXArdelyx, Inc.$718M——+16.8%−49.0%
178Sana Biotechnology, Inc.SANASana Biotechnology, Inc.$709M———−41.4%
179Solid Biosciences Inc.SLDBSolid Biosciences Inc.$707M———+56.2%
180Attovia Therapeutics, Inc.ATTOA clinical-stage biopharmaceutical company developing biotherapeutics for immune-mediated diseases using its ATTOBODY biologics platform.$697M———−32.5%
181Cullinan Therapeutics, Inc.CGEMCullinan Therapeutics, Inc., a clinical-stage biopharmaceutical company, develops therapies for autoimmune diseases and cancer in the United…$695M———+53.9%
182Achieve Life Sciences, Inc.ACHVAchieve Life Sciences, Inc.$692M———+41.8%
183Zevra Therapeutics, Inc.ZVRAZevra Therapeutics, Inc., founded in 2006 and based in Celebration, Florida, is a biopharmaceutical company dedicated to discovering and dev…$688M12.1x—+119.4%+27.5%
184Annexon, Inc.ANNXAnnexon, Inc.$688M———+39.1%
185Nuvectis Pharma, Inc.NVCTNuvectis Pharma, Inc.$683M———+268.8%
186Aura Biosciences, Inc.AURAHeadquartered in Cambridge, Massachusetts, Aura Biosciences, Inc.$680M———+21.3%
1874D Molecular Therapeutics, Inc.FDMT4D Molecular Therapeutics, Inc.$677M——+278,712.1%+12.2%
188ArriVent BioPharma, Inc.AVBPArriVent BioPharma, Inc., a clinical-stage biopharmaceutical company, engages in the identification, development, and commercialization of m…$673M———−25.8%
189Candel Therapeutics, Inc.CADLCandel Therapeutics, Inc.$670M———+77.1%
190Immix Biopharma, Inc.IMMXImmix Biopharma, Inc.$668M———+166.0%
191Wave Life Sciences Ltd.WVEWave Life Sciences Ltd., a clinical-stage biotechnology company, designs, develops, and commercializes ribonucleic acid (RNA) medicines thro…$664M——−30.4%−57.3%
192Kura Oncology, Inc.KURAKura Oncology, Inc., a clinical-stage biopharmaceutical company, develops medicines for the treatment of cancer.$647M——−7.3%−28.4%
193Olema Pharmaceuticals, Inc.OLMAOlema Pharmaceuticals, Inc., a biopharmaceutical enterprise in the clinical development stage, is dedicated to discovering, advancing, and c…$641M———−10.5%
194Design Therapeutics, Inc.DSGNDesign Therapeutics, Inc.$639M———+48.6%
195Geron CorporationGERNGeron Corporation is an advanced-stage biopharmaceutical company dedicated to the creation and market introduction of treatments for myeloid…$636M——+24.4%−8.4%
196Apnimed, Inc.APMDApnimed, Inc.$629M———+14.0%
197Climb Bio, Inc.CLYMClimb Bio, Inc.$591M———+427.7%
198Aclaris Therapeutics, Inc.ACRSAclaris Therapeutics, Inc., a biopharmaceutical firm operating in the United States, is currently in the clinical development phase, focused…$574M——−51.0%+71.8%
199Bicara Therapeutics Inc. Common StockBCAXBicara Therapeutics Inc., a biopharmaceutical firm in the clinical development phase, is headquartered in Boston, Massachusetts.$572M———−40.6%
200Faeth Therapeutics, Inc.FTHFaeth Therapeutics, Inc.$568M———+136.1%
201Ovid Therapeutics Inc.OVIDOvid Therapeutics Inc.$557M——−76.2%+114.3%
202Entera Bio Ltd.ENTXEntera Bio Ltd.$546M———+1.0%
203Adlai Nortye Ltd.ANLAdlai Nortye Ltd.$546M———+563.2%
204SL Science Holding LtdSLBTSL Science Holding Limited manufactures cosmetic skin care and scalp care products.$526M———−80.2%
205Capricor Therapeutics, Inc.CAPRCapricor Therapeutics, Inc.$521M———+43.3%
206Valneva SEVALNValneva SE operates as a specialized biopharmaceutical company, concentrating its efforts on developing and bringing to market preventative…$518M——−26.9%−38.1%
207DiaMedica Therapeutics Inc.DMACDiaMedica Therapeutics Inc.$505M———+50.5%
208Gyre Therapeutics, Inc.GYREGyre Therapeutics, Inc.$505M——+13.5%−35.1%
209REGENXBIO Inc.RGNXREGENXBIO Inc.$503M——+12.0%−31.8%
210Crescent Biopharma, Inc.CBIOCrescent Biopharma, Inc.$503M———+3.4%
211MiMedx Group, Inc.MDXGMiMedx Group, Inc.$483M82.8x—−2.4%−54.8%
212Monopar Therapeutics Inc.MNPRMonopar Therapeutics Inc., a clinical-stage biopharmaceutical company, engages in developing therapeutics for the treatment of cancer in the…$479M———−11.6%
213CytomX Therapeutics, Inc.CTMXCytomX Therapeutics, Inc.$477M——−87.0%−47.7%
214Shattuck Labs, Inc.STTKShattuck Labs, Inc.$464M——−66.6%+135.7%
215Oculis Holding AGOCSOculis Holding AG is a biopharmaceutical company in the clinical development stage, specializing in the creation of innovative eye drop medi…$462M——−6.9%−61.4%
216Eupraxia Pharmaceuticals Inc.EPRXEupraxia Pharmaceuticals Inc., a clinical-stage biotechnology company, focuses on the development of products to address therapeutic areas w…$455M———+23.5%
217Phathom Pharmaceuticals, Inc.PHATPhathom Pharmaceuticals, Inc.$427M——+110.2%−59.7%
218Puma Biotechnology, Inc.PBYIPuma Biotechnology, Inc.$426M15.4x—−2.9%+68.4%
219YD Bio Limited Ordinary SharesYDESYD Bio Limited, a biopharmaceutical company, focuses on regulated diagnostics, life science clinical services, and healthcare product commer…$423M———−36.6%
220Arvinas, Inc.ARVNArvinas, Inc.$419M34.2x—−15.0%−35.9%
221Relmada Therapeutics, Inc.RLMDRelmada Therapeutics, Inc.$416M———+49.4%
222Assembly Biosciences, Inc.ASMBAssembly Biosciences, Inc.$416M37.1x—+125.1%−34.6%
223CorMedix Inc.CRMDCorMedix Inc.$415M2.2x—+280.5%−50.6%
224Prothena Corporation plcPRTAProthena Corporation plc, a late-stage clinical biotechnology company, focuses on discovery and development of novel therapies to treat dise…$409M——+427.3%−20.9%
225Altimmune, Inc.ALTAltimmune, Inc.$405M——+55.0%−47.2%
226Tectonic Therapeutic, Inc.TECXTectonic Therapeutic, Inc.$403M———+8.7%
227Neurogene Inc.NGNENeurogene Inc.$400M———−5.1%
228Editas Medicine, Inc.EDITEditas Medicine, Inc., a clinical stage genome editing company, focuses on developing transformative genomic medicines to treat a range of s…$395M——+20.8%−4.5%
229Zura Bio LimitedZURAZura Bio Limited is a clinical-stage biotechnology company headquartered in San Diego, California, dedicated to pioneering new therapeutic s…$394M———+17.5%
230BlossomHill Therapeutics, Inc.BLSMBlossomhill Therapeutics, Inc.$393M———−6.4%
231ProKidney Corp.PROKProKidney Corp.$383M——+55.2%−59.4%
232C4 Therapeutics, Inc.CCCCC4 Therapeutics, Inc.$381M——+2.3%+30.3%
233AgomAb Therapeutics N.V. American Depositary SharesAGMBAgomAb Therapeutics N.V.$376M———−43.1%
234Indaptus Therapeutics, Inc.INDPIndaptus Therapeutics, Inc.$376M———+23.9%
235Rezolute, Inc.RZLTRezolute, Inc., a late-stage rare disease company, focused on improving outcomes for individuals with hypoglycemia caused by hyperinsulinism…$375M———−59.6%
236Avalo Therapeutics, Inc.AVTXAvalo Therapeutics, Inc.$372M——−86.6%−55.1%
237Lyell Immunopharma, Inc.LYELLyell Immunopharma, Inc., a clinical-stage cell therapy company, develops chimeric antigen receptor (CAR) T-cell product candidates for pati…$364M——−55.0%−16.9%
238Allogene Therapeutics, Inc.ALLOAllogene Therapeutics, Inc.$359M———−1.0%
239Opus Genetics, Inc.IRDOpus Genetics, Inc.$348M——−36.1%+105.9%
240Atea Pharmaceuticals, Inc.AVIRAtea Pharmaceuticals, Inc., a clinical-stage biopharmaceutical company, discovers, develops, and commercializes oral antiviral therapeutics…$346M———+32.6%
241Fennec Pharmaceuticals Inc.FENCFennec Pharmaceuticals Inc.$344M——+77.8%+22.6%
242Orchestra BioMed Holdings, Inc.OBIOOrchestra BioMed Holdings, Inc.$341M——+986.1%+49.1%
243Autolus Therapeutics plcAUTLAutolus Therapeutics plc is a clinical-stage biopharmaceutical entity primarily focused on pioneering T-cell-based immunotherapies for vario…$341M——+292.0%−5.9%
244Contineum Therapeutics, Inc.CTNMContineum Therapeutics, Inc., a clinical stage biopharmaceutical company, engages in developing of small molecules different therapies for n…$337M———−13.5%
245Benitec Biopharma Inc.BNTCBenitec Biopharma Inc., a clinical-stage biotechnology company, focuses on the development of novel genetic medicines.$333M———−20.5%
246Agenus Inc.AGENAgenus Inc.$323M2.6x—+30.5%+86.2%
247Sagimet Biosciences Inc.SGMTSagimet Biosciences Inc., a clinical-stage biopharmaceutical company, develops novel therapeutics called fatty acid synthase (FASN) inhibito…$321M———+28.1%
248Enanta Pharmaceuticals, Inc.ENTAEnanta Pharmaceuticals, Inc.$320M——+0.7%+1.9%
249Eikon Therapeutics, Inc. Common StockEIKNEikon Therapeutics, Inc.$319M———−49.7%
250X4 Pharmaceuticals, Inc.XFORX4 Pharmaceuticals, Inc.$315M——−51.6%−9.4%
251Ocugen, Inc.OCGNOcugen, Inc.$314M——−3.7%−33.0%
252Century Therapeutics, Inc.IPSCCentury Therapeutics, Inc.$304M———+211.1%
253Kyverna Therapeutics, Inc.KYTXKyverna Therapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on developing cell therapies for patients with autoimmune di…$302M———−31.2%
254MapLight Therapeutics, Inc.MPLTMapLight Therapeutics, Inc.$295M———−57.1%
255Arcturus Therapeutics Holdings Inc.ARCTArcturus Therapeutics Holdings Inc.$294M——−79.1%+24.8%
256Vicore Pharma Holding ABVCREVicore Pharma Holding AB is a pharmaceutical company, which engages in the development of drugs with focus on interstitial lung diseases and…$294M——−57.1%−44.1%
257Precision BioSciences, Inc.DTILPrecision BioSciences, Inc.$293M——+3,473.0%+64.6%
258Turn Therapeutics Inc.TTRXTurn Therapeutics Inc., officially known as Global Health Solutions, Inc., is a pharmaceutical enterprise dedicated to developing treatments…$288M———+123.1%
259Nautilus Biotechnolgy, Inc.NAUTNautilus Biotechnology, Inc., a development stage life sciences company, engages in creating a platform technology for quantifying and unloc…$284M———+47.7%
260Fulcrum Therapeutics, Inc.FULCFulcrum Therapeutics, Inc.$282M———−51.6%
261ARS Pharmaceuticals, Inc.SPRYARS Pharmaceuticals, Inc.$277M——+4.1%−66.0%
262SAB Biotherapeutics, Inc.SABSSAB Biotherapeutics, Inc., a clinical-stage biopharmaceutical company, focuses on the development of human polyclonal immunotherapeutic anti…$276M0.8x——−2.3%
263Q32 Bio Inc.QTTBOperating as a clinical-stage biotechnology firm, Q32 Bio Inc.$275M3.3x——+298.7%
264Rocket Pharmaceuticals, Inc.RCKTRocket Pharmaceuticals, Inc., operating alongside its affiliates, is an innovative biotechnology enterprise dedicated to pioneering gene the…$262M———−26.2%
265Vogenx Inc.VOGXVogenx is a clinical-stage biopharmaceutical company focused on the discovery and development of novel therapeutics for the treatment of ser…$259M———+23.5%
266Lineage Cell Therapeutics, Inc.LCTXLineage Cell Therapeutics, Inc., a clinical-stage biotechnology company, developing cell replacement therapies to treat serious medical cond…$258M——+19.9%−41.0%
267Alector, Inc.ALECAlector, Inc.$256M——−82.9%+76.2%
268CAMP4 Therapeutics CorporationCAMPCAMP4 Therapeutics Corporation, a biotechnology firm, was established in 2015 by Richard A.$255M——+40.2%−8.8%
269Scribe Therapeutics Inc.SCTXScribe Therapeutics is a clinical-stage biotechnology company focused on developing in vivo CRISPR-based genetic medicines.$254M———−4.3%
270DBV Technologies S.A.DBVTDBV Technologies S.A., a biopharmaceutical firm based in Montrouge, France, operates at the clinical stage, focusing on the research and dev…$250M———−25.6%
271Bicycle Therapeutics plcBCYCBicycle Therapeutics plc, founded in 2009 and based in Cambridge, UK, is a clinical-stage biopharmaceutical company.$249M——+217.4%−44.5%
272Larimar Therapeutics, Inc.LRMRHeadquartered in Bala Cynwyd, Pennsylvania, Larimar Therapeutics, Inc.$248M———−31.1%
273Evommune, Inc.EVMNEvommune, Inc.$241M———−67.1%
274Abeona Therapeutics Inc.ABEOAbeona Therapeutics Inc.$238M——+6,280.0%−0.5%
275Immuneering CorporationIMRXImmuneering Corporation is a biopharmaceutical company dedicated to developing novel therapeutic candidates in the fields of oncology (cance…$238M———−44.4%
276Lexeo Therapeutics, Inc. Common StockLXEOLexeo Therapeutics, Inc.$237M———−65.7%
277Surrozen, Inc.SRZNSurrozen, Inc., a biotechnology company, discovers and develops drug candidates to selectively modulate the Wnt pathway for tissue repair.$232M——−8.8%+148.0%
278Vanda Pharmaceuticals Inc.VNDAVanda Pharmaceuticals Inc.$231M——+6.0%−13.4%
279Cartesian Therapeutics, Inc.RNACCartesian Therapeutics, Inc., a clinical-stage biotechnology company, provides mRNA cell therapies for the treatment of autoimmune diseases.$228M——+44.0%−0.3%
280AC Immune S.A.ACIUAC Immune S.A.$227M——−39.5%−35.4%
281Bright Minds Biosciences Inc.DRUGBright Minds Biosciences Inc., a biotechnology company, develops therapeutics to improve the lives of patients with severe and life-altering…$227M———−59.0%
282Greenwich LifeSciences, Inc.GLSIGreenwich LifeSciences, Inc.$223M———+84.5%
283Cabaletta Bio, Inc.CABACabaletta Bio, Inc.$220M———−47.6%
284Korro Bio, Inc.KRROKorro Bio, Inc., a biopharmaceutical firm based in Cambridge, Massachusetts, is dedicated to exploring, advancing, and bringing to market ge…$217M——−62.1%−54.7%
285Fate Therapeutics, Inc.FATEFate Therapeutics, Inc.$214M——−23.4%+76.4%
286Eledon Pharmaceuticals, Inc.ELDNEledon Pharmaceuticals, Inc.$212M———−36.5%
287Inhibikase Therapeutics, Inc.IKTInhibikase Therapeutics, Inc.$209M———+0.7%
288Prelude Therapeutics IncorporatedPRLDPrelude Therapeutics, Inc.$208M——+220.3%+166.7%
289Galectin Therapeutics Inc.GALTGalectin Therapeutics Inc.$207M———−43.7%
290Protalix BioTherapeutics, Inc.PLXProtalix BioTherapeutics, Inc., a biopharmaceutical company, engages in the development, production, and commercialization of recombinant th…$205M10.5x—+30.1%+14.4%
291Artiva Biotherapeutics, Inc.ARTVArtiva Biotherapeutics, Inc.$203M———+20.6%
292ADC Therapeutics S.A.ADCTADC Therapeutics S.A.$202M——+2.0%−62.0%
293BioAge Labs Inc.BIOABioAge Labs, Inc., a clinical-stage biopharmaceutical company, develops therapeutic product candidates for metabolic diseases.$201M——+168.1%−28.5%
294Sol-Gel Technologies Ltd.SLGLSol-Gel Technologies Ltd., a pharmaceutical firm currently in its clinical development phase, specializes in the creation and market introdu…$200M——−92.5%+90.6%
295Inventiva S.A.IVAInventiva S.A.$198M——−70.3%−9.1%
296Palisade Bio, Inc.PALIPalisade Bio, Inc., a clinical-stage biopharmaceutical company, engages in developing oral phosphodiesterase-4 inhibitor prodrugs designed f…$197M———−31.9%
297InflaRx N.V.IFRXInflaRx N.V.$192M——−106.2%+8.8%
298ProQR Therapeutics N.V.PRQRProQR Therapeutics N.V.$191M——+12.7%−38.9%
299Entrada Therapeutics, Inc.TRDAEntrada Therapeutics, Inc.$190M——−94.1%−29.6%
300Compugen Ltd.CGENCompugen Ltd., an Israeli-based company established in 1993 and headquartered in Holon, is a clinical-stage enterprise focused on the discov…$186M5.2x—+234.2%+19.5%
301Keros Therapeutics, Inc.KROSKeros Therapeutics, Inc., a biopharmaceutical entity in the clinical development phase, is focused on pioneering and commercializing innovat…$186M——−93.6%−42.1%
302MediWound Ltd.MDWDMediWound Ltd., a biopharmaceutical company, develops, manufactures, and commercializes novel, bio-therapeutic, and non-surgical solutions f…$184M——−40.3%−21.0%
303Whitehawk Therapeutics IncWHWKWhitehawk Therapeutics, Inc., a clinical-stage oncology therapeutics company that develops technologies to establish tumor biology for cance…$178M———+49.0%
304Upstream Bio, Inc.UPBUpstream Bio, Inc.$177M——+16.0%−86.3%
305PepGen Inc.PEPGPepGen Inc., a clinical-stage biotechnology company, develops oligonucleotide therapeutics for the treatment of severe neuromuscular and neu…$171M———−41.3%
306Invivyd, Inc.IVVDAdagio Therapeutics, Inc., a biopharmaceutical firm in its clinical development phase, operates within the United States, specializing in th…$166M——+26.3%−63.4%
307Canton Strategic Holdings IncCNTNCanton Strategic Holdings Inc., which was formerly known as Tharimmune, Inc.$164M———−50.4%
308Niagen Bioscience IncNAGENiagen Bioscience, Inc.$164M10.7x—+11.0%−68.6%
309BridgeBio Oncology Therapeutics Inc.BBOTBridgeBio Oncology Therapeutics, Inc., a clinical-stage biotechnology company, engages in the development of small-molecule therapeutics for…$164M———−83.3%
310Innate Pharma S.A.IPHAInnate Pharma S.A.$161M——−91.4%−20.0%
311Oramed Pharmaceuticals Inc.ORMPOramed Pharmaceuticals Inc., founded in 2002 and based in New York, New York, specializes in the development of groundbreaking pharmaceutica…$161M0.9x6.48%—+88.3%
312ALX Oncology Holdings Inc.ALXOALX Oncology Holdings Inc., a clinical-stage immuno-oncology company, focuses on developing therapies for cancer patients in the United Stat…$160M———−2.1%
313Sutro Biopharma, Inc.STROSutro Biopharma, Inc.$160M——−56.3%+2.1%
314AN2 Therapeutics, Inc.ANTXAN2 Therapeutics, Inc.$151M———+257.1%
315MacroGenics, Inc.MGNXMacroGenics, Inc., a clinical-stage biopharmaceutical company, discovers, develops, manufactures, and commercializes antibody-based therapeu…$148M——+2.3%+71.3%
316Sionna Therapeutics, Inc.SIONSionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosi…$148M———−90.5%
317Korsana Biosciences, Inc.KRSACyclerion Therapeutics, Inc.$145M——−12.6%+162.5%
318Yarrow Bioscience IncYARWYarrow Bioscience is a clinical-stage biotechnology company focused on developing transformative therapies for autoimmune thyroid diseases.$145M—128.85%+1.3%−11.0%
319NervGen Pharma Corp. Common stockNGENNervGen Pharma Corp., a biotechnology company, engages in the discovery, development, and commercialization of pharmaceutical treatments to…$143M———−62.1%
320Atrium Therapeutics, Inc.RNAAtrium Therapeutics, Inc.$143M———−47.0%
321Jyong Biotech Ltd. Ordinary SharesMENSJyong Biotech Ltd.$137M———−95.2%
322Compass Therapeutics, Inc.CMPXCompass Therapeutics, Inc.$137M———−81.0%
323Cue Biopharma, Inc.CUECue Biopharma, Inc.$136M——+354.4%−12.8%
324Protara Therapeutics, Inc.TARAProtara Therapeutics, Inc.$136M———−46.4%
325Veraxa Biotech Holding AGVRXAVeraxa Biotech AG develops antibody-based therapeutics and antibody-drug conjugates for cancer treatment.$134M———−91.0%
326Spruce Biosciences, Inc.SPRBSpruce Biosciences, Inc., founded in 2014 and situated in Daly City, California, operates as a biopharmaceutical enterprise.$134M———−61.0%
327MaxCyte, Inc.MXCTMaxCyte, Inc., a life sciences company, discovers, develops, and commercializes cell therapeutics in the United States and internationally.$130M——−13.2%−14.3%
328Alpha Cognition IncACOGAlpha Cognition Inc., a biopharmaceutical company, engages in the development of treatments for patients suffering from neurodegenerative di…$129M——+232.7%+45.4%
329Armata Pharmaceuticals, Inc.ARMPArmata Pharmaceuticals, Inc.$128M——−52.0%−40.1%
330PolyPid Ltd.PYPDPolyPid Ltd.$125M———+61.6%
331Humacyte, Inc.HUMAHumacyte, Inc.$125M——−73.6%−65.8%
332Nkarta, Inc.NKTXNkarta, Inc., a clinical-stage biopharmaceutical company, develops and commercializes natural killer cell therapies for cancer and autoimmun…$124M———−12.2%
333Zentalis Pharmaceuticals, Inc.ZNTLZentalis Pharmaceuticals, Inc.$122M———+32.3%
334Molecular Partners AGMOLNMolecular Partners AG operates as a clinical-stage biopharmaceutical company, specializing in the identification, advancement, and commercia…$120M———−32.8%
335Coherus Oncology, Inc.CHRSCoherus Oncology, Inc.$119M——−64.3%−48.3%
336Codexis, Inc.CDXSCodexis, Inc.$118M——+35.9%−47.1%
337enGene Holdings Inc.ENGNOperating through its subsidiary, enGene, Inc., enGene Holdings Inc.$117M———−70.9%
338OnKure Therapeutics, Inc.OKUROnKure, Inc., established in 2011 and based in Boulder, Colorado, operates as a biopharmaceutical company primarily engaged in the creation…$116M———−9.3%
339Minerva Neurosciences, Inc.NERVMinerva Neurosciences, Inc.$116M———−33.5%
340Voyager Therapeutics, Inc.VYGRVoyager Therapeutics, Inc.$115M——−19.1%−55.8%
341Akebia Therapeutics, Inc.AKBAAkebia Therapeutics, Inc., established in 2007 and headquartered in Cambridge, Massachusetts, is a biopharmaceutical company focused on disc…$111M——+7.5%−80.0%
342Foghorn Therapeutics Inc.FHTXFoghorn Therapeutics Inc.$111M——+52.0%−53.2%
343Anixa Biosciences, Inc.ANIXAnixa Biosciences, Inc.$110M———−21.8%
344LENZ Therapeutics, Inc.LENZLENZ Therapeutics, Inc.$110M——+329.5%−84.8%
345Cellectis S.A.CLLSCellectis S.A.$108M——+0.5%−65.8%
346Anavex Life Sciences Corp.AVXLOperating as a clinical-stage biopharmaceutical entity, Anavex Life Sciences Corp.$107M———−84.5%
347Outlook Therapeutics, Inc.OTLKOutlook Therapeutics, Inc.$106M——−177.3%−63.0%
348Immunic, Inc.IMUXImmunic, Inc.$106M———+10.6%
349Pyxis Oncology, Inc.PYXSPyxis Oncology, Inc.$105M——+291.4%−58.9%
350NovaBridge BiosciencesNBPNovaBridge Biosciences, a biotechnology firm, primarily focuses on pioneering immuno-oncology treatments for cancer patients within the Unit…$105M———−78.3%
351TuHURA Biosciences, Inc.HURATuHURA Biosciences, Inc.$104M———−33.5%
352NRx Pharmaceuticals, Inc.NRXPNRx Pharmaceuticals, Inc.$103M———−10.9%
353Neonc Technologies Holdings, Inc.NTHINeOnc Technologies Holdings, Inc.$101M———−64.6%
354Black Diamond Therapeutics, Inc.BDTXBlack Diamond Therapeutics, Inc.$99.4M———−56.4%
355Unicycive Therapeutics, Inc.UNCYUnicycive Therapeutics, Inc.$97.2M———−20.8%
356Vivani Medical, Inc.VANIVivani Medical, Inc., a clinical-stage biopharmaceutical company, engages in the development of miniaturized and subdermal drug implants tha…$96.5M———−27.2%
357Equillium, Inc.EQEquillium, Inc.$95.7M———+19.8%
358Milestone Pharmaceuticals Inc.MISTMilestone Pharmaceuticals Inc.$95M———−55.7%
359Neumora Therapeutics, Inc. Common StockNMRANeumora Therapeutics, Inc.$94.6M———−80.5%
360Polaryx Therapeutics, Inc. Common StockPLYXPolaryx Therapeutics, Inc.$91.7M———−94.4%
361Seer, Inc.SEERSeer, Inc.$90.3M——−13.3%−24.5%
362Cibus, Inc.CBUSCibus, Inc.$90.2M——−6.0%−5.6%
363ImmuCell CorporationICCCImmuCell Corporation functions as an animal health enterprise, specializing in the creation, manufacturing, and commercialization of offerin…$89M115.8x—+8.5%+55.3%
364Genelux CorporationGNLXGenelux Corporation is a clinical-stage biopharmaceutical company focused on pioneering advanced oncolytic viral immunotherapies for patient…$88.7M———−63.0%
365Tiziana Life Sciences LtdTLSATiziana Life Sciences Ltd is a biotechnology firm dedicated to the research and advancement of novel molecular therapies for human ailments,…$87.7M———−61.7%
366Rallybio CorporationRLYBRallybio Corporation is a clinical-stage biotechnology firm dedicated to discovering and bringing to market transformative therapies for ind…$84.8M2.0x—−15.1%+208.2%
367Inovio Pharmaceuticals, Inc.INOInovio Pharmaceuticals, Inc.$83.9M———−46.0%
368vTv Therapeutics Inc.VTVTvTv Therapeutics Inc.$83.2M——+216,600.0%−17.4%
369Tenaya Therapeutics, Inc.TNYATenaya Therapeutics, Inc., a clinical-stage biotechnology company, discovers, develops, and delivers therapies for heart disease in the Unit…$82.1M———−73.3%
370Tonix Pharmaceuticals Holding Corp.TNXPTonix Pharmaceuticals Holding Corp.$81.3M——+196.0%−72.8%
371Atara Biotherapeutics, Inc.ATRAFounded in 2012 and headquartered in South San Francisco, California, Atara Biotherapeutics, Inc.$79M——−96.7%−33.4%
372NeurAxis, Inc.NRXSNeurAxis, Inc.$78.4M——+65.2%+146.6%
373Adagene Inc.ADAGAdagene Inc.$75.3M——+1,054.7%+24.2%
374OKYO Pharma LimitedOKYOOKYO Pharma Limited is a biopharmaceutical firm operating at the preclinical stage, dedicated to developing innovative treatments for indivi…$75M———−45.6%
375MediciNova, Inc.MNOVMediciNova, Inc.$71.9M——+583.9%+4.3%
376Coya Therapeutics, Inc.COYACoya Therapeutics, Inc.$70.1M——+1,793.8%−48.1%
377Conexeu Sciences Inc.CNXUConexeu Sciences Inc.$69.7M———−69.8%
378Acrivon Therapeutics, Inc. Common StockACRVAcrivon Therapeutics, Inc.$69M———−19.5%
379PDS Biotechnology CorporationPDSBPDS Biotechnology Corporation is a clinical-stage biopharmaceutical firm dedicated to advancing innovative, multi-functional immunotherapies…$68.7M———+38.4%
380Nutriband Inc.NTRBNutriband Inc.$67.5M——−37.3%+0.4%
381PMV Pharmaceuticals, Inc.PMVPPMV Pharmaceuticals, Inc.$67.2M———+0.8%
382Champions Oncology, Inc.CSBRChampions Oncology, Inc.$66.7M——+6.7%−30.4%
383MAIA Biotechnology, Inc.MAIAMAIA Biotechnology, Inc.$65.4M———−3.6%
384Cognition Therapeutics, Inc.CGTXCognition Therapeutics, Inc.$65.3M———−58.6%
385Cingulate Inc.CINGCingulate Inc.$61.9M———+15.8%
386Cardiff Oncology, Inc.CRDFCardiff Oncology, Inc., a clinical-stage biotechnology company, develops novel therapies for the treatment of various cancers in the United…$61.9M——−7.0%−64.7%
387Fortress Biotech, Inc.FBIOFortress Biotech, Inc.$61.7M0.6x—+15.5%−26.6%
388Spero Therapeutics, Inc.SPROSpero Therapeutics, Inc.$60M7.4x—−7.0%−56.9%
389Gossamer Bio, Inc.GOSSGossamer Bio, Inc., a clinical-stage biopharmaceutical company, focuses on developing and commercializing seralutinib for the treatment of p…$59.7M——+32.4%−94.7%
390Corbus Pharmaceuticals Holdings, Inc.CRBPCorbus Pharmaceuticals Holdings, Inc.$59.4M———−70.6%
391XBiotech Inc.XBITXBiotech Inc.$57.6M———−20.9%
392Kalaris Therapeutics IncKLRSKalaris Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development and commercialization of treatments for p…$57.6M———−48.8%
393Xilio Therapeutics, Inc.XLOXilio Therapeutics, Inc.$56.7M——+327.3%−25.9%
394Clene Inc.CLNNClene Inc.$56.1M——−31.1%−57.3%
395Boundless Bio, Inc.BOLDBoundless Bio, Inc., a clinical-stage oncology company, focuses on developing innovative cancer therapies aimed at addressing the significan…$56M———+95.2%
396Heron Therapeutics, Inc.HRTXHeron Therapeutics, Inc.$55.6M——+1.0%−73.4%
397Apollomics, Inc.APLMApollomics, Inc., a biotechnology enterprise established in 2015 and headquartered in Foster City, California, conducts its research and dev…$55.4M——+660.3%+42.6%
398Alps Group IncALPSAlps Group Inc.$54.9M———−62.0%
399Verrica Pharmaceuticals Inc.VRCAVerrica Pharmaceuticals Inc., a dermatology therapeutics company, engages in the development and commercialization of medications for the tr…$54.8M——+106.2%−10.9%
400Rein Therapeutics Inc.RNTXRein Therapeutics Inc.$52.9M———−60.7%
401MiNK Therapeutics, Inc.INKTMiNK Therapeutics, Inc.$52.8M———−24.2%
402Telomir Pharmaceuticals, Inc. Common StockTELOTelomir Pharmaceuticals, Inc.$52.3M———−47.4%
403RenovoRx, Inc.RNXTRenovoRx, Inc.$51M——+198.5%+17.0%
404Pliant Therapeutics, Inc.PLRXPliant Therapeutics, Inc.$50.1M———−47.1%
405MindWalk Holdings Corp.HYFTMindWalk Holdings Corp.$49.9M——−14.7%−37.6%
406Werewolf Therapeutics, Inc.HOWLWerewolf Therapeutics, Inc.$49.1M———−15.8%
407Dogwood Therapeutics, Inc.DWTXDogwood Therapeutics, Inc.$48.9M———−75.4%
408Caribou Biosciences, Inc.CRBUCaribou Biosciences, Inc.$48.1M——+10.0%−79.0%
409iBio, Inc.IBIOiBio, Inc., a United States-based biotechnology firm, delivers contract development and manufacturing (CDMO) services to its collaborators a…$47.5M——−75.0%−46.9%
410OS Therapies IncorporatedOSTXOS Therapies Incorporated, a clinical stage biopharmaceutical company, focuses on the identification, development, and commercialization of…$46.8M———−45.1%
411ImageneBio IncIMAImageneBio, Inc., a clinical-stage biopharmaceutical company, develops therapeutics for patients with immunological, autoimmune and inflamma…$46.6M———−51.1%
412Instil Bio, Inc.TILInstil Bio, Inc., a biopharmaceutical company, focuses on identifying and advancing therapeutic opportunities.$46.3M———−54.5%
413Connect Biopharma Holdings LimitedCNTBConnect Biopharma Holdings Limited is a clinical-stage biopharmaceutical company dedicated to discovering and advancing immune modulators.$45.9M——−84.7%−56.1%
414Mereo BioPharma Group plcMREOMereo BioPharma Group plc, a London-based biopharmaceutical firm established in 2015, specializes in developing and commercializing innovati…$45.2M———−83.9%
415Actinium Pharmaceuticals, Inc.ATNMActinium Pharmaceuticals, Inc.$45M4.0x——+8.3%
416Tenax Therapeutics, Inc.TENXTenax Therapeutics, Inc.$44.8M———−75.6%
417NOMAD Power Solutions, Inc.NMADNOMAD Power Solutions, Inc., through its wholly owned subsidiary NOMAD Transportable Power Systems, provides transportable, utility-grade ba…$44.5M———−38.5%
418Oncolytics Biotech Inc.ONCYOncolytics Biotech Inc., a clinical-stage biopharmaceutical company, engages in the research, development, and commercialization of oncology…$44.1M———−56.5%
419Gain Therapeutics, Inc.GANXGain Therapeutics, Inc.$43.9M———−45.8%
420Eloxx Pharmaceuticals, Inc.ELOXEloxx Pharmaceuticals is a clinical-stage biopharmaceutical firm that specializes in developing therapeutic solutions through ribosome modul…$42.7M———+24.4%
421Alterity Therapeutics LimitedATHEAlterity Therapeutics Limited, an Australian biopharmaceutical firm, focuses on the discovery and development of novel drug treatments for v…$41.2M——−31.5%−30.6%
422Biomea Fusion, Inc.BMEABiomea Fusion, Inc., a clinical-stage diabetes and obesity medicines company, focuses on the discovery and development of oral drugs to trea…$41M———−56.4%
423eXoZymes, Inc.EXOZeXoZymes, Inc.$40.8M———−67.4%
424Aldeyra TheALDXAldeyra Therapeutics, Inc., a biotechnology company, discovers and develops therapies designed to treat immune-mediated diseases.$38.2M———−86.8%
425ProMIS Neurosciences, Inc.PMNProMIS Neurosciences, Inc.$37.3M———−57.4%
426Elutia IncELUTElutia Inc., a commercial-stage company, focuses on developing drug-eluting biomatrix products for use in surgical reconstruction and relate…$37.1M0.6x—−48.8%−11.1%
427Veru Inc.VERUVeru Inc.$36.1M———−15.9%
428Annovis Bio, Inc.ANVSAnnovis Bio, Inc.$36.1M———−57.5%
429Pelthos Therapeutics Inc.PTHSPelthos Therapeutics Inc.$35.8M———−75.0%
430Rani Therapeutics Holdings, Inc.RANIRani Therapeutics Holdings, Inc.$35.7M——+306.4%−75.9%
431Impact BioMedical Inc.IBOHouston, Texas-based Impact BioMedical Inc., founded in 2018, focuses on discovering and developing innovative products and therapeutic opti…$35.5M——+400.0%−39.0%
432GridAI Technologies Corp.GRDXGridAI Technologies Corp., together with its subsidiaries, designs and develops an artificial intelligence (AI)-driven software and device p…$35.1M———+42.2%
433BriaCell Therapeutics Corp.BCTXBriaCell Therapeutics Corp.$34.5M———−59.8%
434NanoViricides, Inc.NNVCNanoViricides, Inc.$33.7M———−30.5%
435IRulya Therapeutics Inc.IRLAIRulya Therapeutics is a clinical-stage biopharmaceutical company developing LAM-001, an inhaled formulation of rapamycin, for pulmonary dis…$31.5M———−90.3%
436INmune Bio, Inc.INMBINmune Bio, Inc.$31.4M———−30.7%
437Lite Strategy, Inc.LITSLite Strategy, Inc.$31M———−44.6%
438EyePoint Pharmaceuticals, Inc.EYPTEyePoint Pharmaceuticals, Inc.$30.2M——−94.6%−96.8%
439Grace Therapeutics, Inc.GRCEGrace Therapeutics, Inc.$30.1M———−39.1%
440Elicio Therapeutics, Inc.ELTXElicio Therapeutics, Inc.$28.8M———−83.4%
441Adicet Bio, Inc.ACETAdicet Bio, Inc.$28.6M———−71.8%
442Incannex Healthcare LimitedIXHLIncannex Healthcare Limited is an Australian company dedicated to the research, development, and commercialization of medicinal cannabinoid…$26.8M———−79.5%
443Metagenomi, Inc. Common StockMGXMetagenomi, Inc.$26.8M——−59.8%−68.0%
444ABVC BioPharma, Inc.ABVCABVC BioPharma, Inc.$25.9M——−303.4%−65.9%
445Aardvark Therapeutics, Inc. Common StockAARDAardvark Therapeutics, Inc.$25.6M———−88.1%
446CEL-SCI CorporationCVMCEL-SCI Corporation (CVM) focuses on the research and development of immune-based therapies to combat cancer and various infectious diseases…$25.5M———−78.2%
447Aligos Therapeutics, Inc.ALGSAligos Therapeutics, Inc.$25.4M——+893.0%−42.7%
448BeyondSpring Inc.BYSIBeyondSpring Inc.$25.1M———−68.2%
449Celularity Inc.CELUCelularity Inc.$24.7M——−62.8%−55.0%
450Immutep LimitedIMMPImmutep Limited, a biotechnology company, engages in developing novel Lymphocyte Activation Gene-3 related immunotherapies for cancer and au…$24.6M——+195.3%−89.9%
451NextCure, Inc.NXTCNextCure, Inc.$24.4M———−45.7%
452Tevogen Bio Holdings Inc.TVGNTevogen Bio Holdings Inc.$23.3M———−76.2%
453Filana Therapeutics, Inc.FLNAFilana Therapeutics, Inc.$21.9M———−62.9%
454CervoMed Inc.CRVOCervoMed Inc., a clinical-stage biotechnology company, engages in the development and commercialization of treatments for age-related neurol…$21.5M———−80.5%
455Enlivex Therapeutics Ltd.ENLVEnlivex Therapeutics Ltd., established in 2005 and based in Nes Ziona, Israel, operates as a clinical-stage biotechnology firm dedicated to…$21.4M0.0x——−99.5%
456Atossa Therapeutics, Inc.ATOSAtossa Therapeutics, Inc.$21.2M———−82.7%
457BioStem Technologies, Inc.BSEMBioStem Technologies, Inc.$21.1M——−119.6%−70.8%
458Serina Therapeutics, Inc.SERSerina Therapeutics, Inc., a biotechnology firm, focuses on creating pharmaceutical treatments for neurological conditions and pain.$20.7M———−66.5%
459IGC Pharma, Inc.IGCIGC Pharma, Inc.$20.7M——−15.4%−48.1%
460Edesa Biotech, Inc.EDSAEdesa Biotech, Inc.$20.6M———+25.9%
461Cocrystal Pharma, Inc.COCPCocrystal Pharma, Inc.$20M———+3.0%
462Seres Therapeutics, Inc.MCRBSeres Therapeutics, Inc.$19.7M———−85.7%
463Pasithea Therapeutics Corp.KTTAPasithea Therapeutics Corp.$19.3M———−19.9%
464Evaxion Biotech A/SEVAXEvaxion Biotech A/S is a clinical-stage biotechnology firm dedicated to creating artificial intelligence-driven immunotherapies.$18.9M——+135.9%−52.1%
465Jasper Therapeutics, Inc.JSPRJasper Therapeutics, Inc., a clinical-stage biotechnology company, focuses on developing therapeutics targeting mast and hematopoietic stem…$18.7M———−69.3%
466Context Therapeutics Inc.CNTXContext Therapeutics Inc., a biopharmaceutical company, develops products for the treatment of solid tumors.$17.8M———−81.9%
467LeonaBio, Inc.LONALeonaBio, Inc.$17.4M———+10.1%
468Akari Therapeutics, PlcAKTXAkari Therapeutics, Plc, an oncology company, develops antibody-drug conjugates (ADC) for cancer-killing toxins.$16.9M———−70.1%
469Estrella Immunopharma, Inc.ESLAEstrella Immunopharma, Inc.$16.3M———−86.4%
470Acumen Pharmaceuticals, Inc.ABOSAcumen Pharmaceuticals Inc.$16.2M———−88.2%
471aTyr Pharma, Inc.ATYRaTyr Pharma, Inc., a biopharmaceutical firm established in San Diego, California, in 2005, is dedicated to the discovery and advancement of…$15.6M———−79.4%
472Allarity Therapeutics, Inc.ALLRAllarity Therapeutics, Inc.$15.4M———−13.1%
473Kyntra Bio, Inc.KYNBKyntra Bio, Inc.$15.1M0.1x——−66.1%
474Neuphoria Therapeutics Inc.NEUPNeuphoria Therapeutics, Inc.$15M——−92.3%−35.0%
475Citius Pharmaceuticals, Inc.CTXRCitius Pharmaceuticals, Inc.$15M———−56.0%
476Marker Therapeutics, Inc.MRKRMarker Therapeutics, Inc.$14.9M——−77.1%+1.4%
477Obsidian Therapeutics Inc.OBXA clinical-stage biopharmaceutical company harnessing novel protein-regulation technology to develop engineered tumor-infiltrating lymphocyt…$14.4M———−30.3%
478Dyadic International, Inc.DYAIDyadic International, Inc.$13.6M——+1.5%−65.3%
479Quantum BioPharma Ltd.QNTMQuantum BioPharma Ltd., a biopharmaceutical firm headquartered in Toronto, Canada, is dedicated to the discovery and advancement of biotechn…$13.5M———−75.5%
480Pluri Inc.PLURPluri Inc., a biotechnology company established in 2001 and headquartered in Haifa, Israel, specializes in developing innovative placenta-de…$13.3M——−24.0%−62.0%
481Adial Pharmaceuticals, Inc.ADILAdial Pharmaceuticals, Inc.$13.3M———−46.8%
482Lipocine Inc.LPCNLipocine Inc.$12.9M——−62.7%−40.5%
483BioCardia, Inc.BCDABioCardia, Inc.$12.9M———−33.6%
484Passage Bio, Inc.PASGPassage Bio, Inc.$12.8M———−38.9%
485Tvardi Therapeutics, Inc.TVRDTvardi Therapeutics, Inc., a clinical-stage biopharmaceutical company, engages in the development of novel, oral, and small molecule therapi…$12.8M———−75.7%
486Bolt Biotherapeutics, Inc.BOLTBolt Biotherapeutics, Inc.$12.6M——+12.8%+36.8%
487Polyrizon Ltd.PLRZPolyrizon Ltd.$12.4M———+100.8%
488Fractyl Health, Inc.GUTSFractyl Health, Inc., a metabolic therapeutics company, develops therapies for the treatment of type 2 diabetes (T2D) and obesity.$12.3M———−92.9%
489TScan Therapeutics, Inc.TCRXTScan Therapeutics, Inc., a clinical-stage biotechnology company, develops T cell receptor-engineered T cell (TCR-T) therapies for the treat…$11.9M——+2.2%−83.8%
490Cellectar Biosciences, Inc.CLRBCellectar Biosciences is a biopharmaceutical firm engaged in the research, development, and market introduction of therapeutic agents to com…$11.8M———−63.6%
491Kazia Therapeutics Ltd ADRKZIAKazia Therapeutics Limited, together with its subsidiaries, operates as an oncology-focused biotechnology company in Israel.$11.6M——+250,944.3%−4.3%
492BioVie Inc.BIVIBioVie Inc.$11.5M———−11.3%
493Palatin Technologies, Inc.PTNPalatin Technologies, Inc., a biopharmaceutical company, develops first-in-class medicines based on molecules that modulate the activity of…$11.2M———−17.7%
494Vyome Holdings, Inc.HINDVyome Holdings, Inc.$11.1M——−98.0%−72.1%
495CytoMed Therapeutics LimitedGDTCCytoMed Therapeutics Limited is a biopharmaceutical company in the pre-clinical development phase, founded in 2018 and based in Singapore.$10.2M——+49.1%−57.9%
496Curanex Pharmaceuticals Inc Common StockCURXCuranex Pharmaceuticals Inc.$9.7M———−49.3%
497Dare Bioscience, Inc.DAREDaré Bioscience, Inc.$9.6M———−64.7%
498MetaVia Inc.MTVAHeadquartered in Cambridge, Massachusetts, MetaVia Inc.$9.4M———−84.7%
499Chemomab Therapeutics Ltd.CMMBChemomab Therapeutics Ltd.$9.4M———−48.8%
500Phio Pharmaceuticals Corp.PHIOPhio Pharmaceuticals Corp., a clinical stage biopharmaceutical company, engages in the development of immuno-oncology therapeutics in the Un…$9.3M———−45.9%
501Lisata Therapeutics, Inc.LSTALisata Therapeutics, Inc.$9.3M——−90.7%−56.2%
502Satellos Bioscience Inc.MSLESatellos Bioscience Inc., a biotechnology company, develops medicines to treat degenerative muscle diseases primarily in Canada and Australi…$9.3M———−3.4%
503IN8bio, Inc.INABIN8bio, Inc.$9.1M———−44.2%
504Moleculin Biotech, Inc.MBRXMoleculin Biotech, Inc.$8.9M———−96.2%
505AEON Biopharma, Inc.AEONAEON Biopharma, Inc.$8.8M———−81.9%
506BriaCell Therapeutics Corp.BCTXLBriaCell Therapeutics Corp.$8.5M———−6.2%
507BioLineRx Ltd.BLRXBioLineRx Ltd., an Israeli biopharmaceutical firm established in 2003 and based in Hevel Modi'in, focuses its clinical-stage development eff…$8.5M———−48.6%
508Lantern Pharma Inc.LTRNLantern Pharma Inc.$8.5M———−83.1%
509Intensity Therapeutics, Inc.INTSIntensity Therapeutics, Inc.$8.1M———−75.3%
510Actuate Therapeutics IncACTUActuate Therapeutics, Inc.$7.9M———−94.7%
511Theriva Biologics, Inc.TOVXTheriva Biologics Inc.$7.6M———−39.1%
512Tempest Therapeutics, Inc.TPSTTempest Therapeutics Inc.$7.6M———−96.0%
513CollPlant Biotechnologies Ltd.CLGNCollPlant Biotechnologies Ltd.$7.5M——−86.8%−81.8%
514Lexaria Bioscience Corp.LEXXLexaria Bioscience Corp.$7.4M——−68.5%−72.2%
515Soligenix, Inc.SNGXSoligenix, Inc., a biopharmaceutical firm in its advanced development stages, concentrates on bringing innovative products to market within…$7.3M———−73.8%
516VistaGen Therapeutics, Inc.VTGNVistaGen Therapeutics, Inc.$7.3M——+287.3%−95.9%
517Quoin Pharmaceuticals, Ltd.QNRXQuoin Pharmaceuticals, Ltd.$7.1M———−58.7%
518Artelo Biosciences, Inc.ARTLArtelo Biosciences, Inc.$6.8M———−88.3%
519Alzamend Neuro IncALZNAlzamend Neuro, Inc., a clinical-stage biopharmaceutical company, focuses on developing various products for the treatment of neurodegenerat…$6.8M———−44.0%
520FibroBiologics, Inc. Common StockFBLGFibroBiologics, Inc.$6.5M———−85.4%
521Aprea Therapeutics, Inc.APREAprea Therapeutics, Inc.$6.5M———−56.9%
522Ensysce Biosciences, Inc.ENSCEnsysce Biosciences, Inc.$6.4M———−84.1%
523Enveric Biosciences, Inc.ENVBEnveric Biosciences, Inc.$6.4M———−76.4%
524Kiora Pharmaceuticals, Inc.KPRXKiora Pharmaceuticals, Inc., a specialty pharmaceutical firm operating at the clinical stage, is dedicated to the creation and commercializa…$6.4M———−37.9%
525Exicure, Inc.XCURExicure, Inc.$6.2M———−77.7%
526AIM ImmunoTech Inc.AIMAIM ImmunoTech Inc., an immuno-pharmaceutical company based in Ocala, Florida, focuses on discovering and advancing treatments for a diverse…$6.2M——−21.5%−90.1%
527Alaunos Therapeutics, Inc.TCRTAlaunos Therapeutics, Inc.$6M——−50.0%−29.3%
528Acurx Pharmaceuticals, Inc.ACXPAcurx Pharmaceuticals, Inc.$5.9M———−78.8%
529CNS Pharmaceuticals, Inc.CNSPCNS Pharmaceuticals, Inc.$5.7M———−43.3%
530NuCana plcNCNANuCana plc is a clinical-stage biopharmaceutical firm dedicated to pioneering advanced therapies for oncology.$5.7M———−74.2%
531GT Biopharma, Inc.GTBPGT Biopharma, Inc.$5.6M———−68.1%
532Longeveron Inc.LGVNLongeveron Inc.$5.5M——−42.7%−76.5%
533Processa Pharmaceuticals, Inc.PCSAProcessa Pharmaceuticals, Inc.$5.4M———−75.6%
534Immuron LimitedIMRNImmuron Limited is a biopharmaceutical company focused on the discovery, development, and global commercialization of polyclonal antibodies,…$5.4M——+28.7%−49.9%
535SeaStar Medical Holding CorporationICUSeaStar Medical Holding Corporation is a medical device company dedicated to providing innovative solutions and services designed to combat…$5.3M——+123.6%−59.2%
536Ainos, Inc.AIMDAinos, Inc.$5.2M——−87.7%−76.1%
537Pulmatrix, Inc.PULMPulmatrix, Inc.$5M———−71.1%
538Senti Biosciences, Inc.SNTISenti Biosciences, Inc.$5M———−91.2%
539Cardio Diagnostics Holdings, Inc.CDIOCardio Diagnostics Holdings, Inc.$4.9M——−25.9%−55.6%
540Imunon, Inc.IMNNImunon, Inc.$4.7M———−78.7%
541Azitra, Inc.AZTRAzitra, Inc.$4.4M———−83.2%
542Skye Bioscience, Inc.SKYESkye Bioscience, Inc., a clinical-stage biotechnology company, focuses on developing molecules that modulate G-protein-coupled receptors (GP…$4.4M———−91.9%
543Xenetic Biosciences, Inc.XBIOXenetic Biosciences, Inc.$4.4M——+33.3%−31.2%
544CalciMedica, Inc.CALCCalciMedica, Inc., a clinical-stage biotechnology company headquartered in La Jolla, California, is focused on creating treatments for life-…$4.3M———−91.1%
545GRI Bio, Inc.GRIGRI Bio, Inc., a clinical-stage biopharmaceutical company, focuses on discovering, developing, and commercializing therapies that target dis…$4.1M———−96.2%
546Apimeds Pharmaceuticals US, IncAPUSApimeds Pharmaceuticals US, Inc.$4.1M———−89.2%
547PharmaCyte Biotech, Inc.PMCBPharmaCyte Biotech, Inc.$3.9M———−57.2%
548Dermata Therapeutics, Inc.DRMADermata Therapeutics, Inc.$3.8M———−74.1%
549Addex Therapeutics LtdADXNAddex Therapeutics Ltd, a biopharmaceutical firm in a developmental phase, operates out of Switzerland, focusing on the discovery, advanceme…$3.6M——−48.1%−66.9%
550Cadrenal Therapeutics, Inc. Common StockCVKDCadrenal Therapeutics, Inc.$3.5M———−92.0%
551Liminatus Pharma, Inc. Class A Common StockLIMNLiminatus Pharma, Inc.$3.4M———−96.0%
552Traws Pharma, Inc.TRAWTraws Pharma, Inc., a biopharmaceutical firm in the clinical development stage, is dedicated to creating novel small-molecule medications de…$3.4M——+606.3%−89.1%
553NeuroSense Therapeutics Ltd.NRSNNeuroSense Therapeutics Ltd.$3.2M———−91.8%
554Ernexa Therapeutics Inc.ERNAErnexa Therapeutics Inc.$3.1M———−95.6%
555KALA BIO, Inc.KALAKala Bio, Inc.$3M———−99.6%
556Jupiter Neurosciences, Inc.JUNSJupiter Neurosciences, Inc.$2.9M———−97.8%
557Clearmind Medicine Inc.CMNDClearmind Medicine Inc.$2.8M———−99.8%
558Aptevo Therapeutics Inc.APVOAptevo Therapeutics Inc.$2.7M———−95.3%
559Medicus Pharma Ltd. Common StockMDCXMedicus Pharma Ltd., a biotechnology and life sciences enterprise, is dedicated to expediting the progression of innovative and groundbreaki…$2.7M———−98.5%
560Mustang Bio, Inc.MBIOMustang Bio, Inc., a clinical-stage biopharmaceutical company, focuses on translating cell therapies into cures for difficult-to-treat cance…$2.7M———−68.7%
561Onconetix, Inc.ONCOOnconetix, Inc.$2.5M——−51.3%−99.5%
562MBody AI Ltd.MBAIMBody AI Ltd.$2.4M0.5x——−71.5%
563VivoSim Labs, Inc.VIVSVivoSim Labs, Inc., a pharmaceutical and biotechnology services company, provides testing of drugs and drug candidates in three-dimensional…$2.3M——−21.1%−93.5%
564Evogene Ltd.EVGNEvogene Ltd., along with its subsidiaries, operates as a computational biology firm.$2.3M——−80.4%−76.6%
565Revelation Biosciences, Inc.REVBRevelation Biosciences, Inc.$2.2M———−86.2%
566Can-Fite BioPharma Ltd.CANFCan-Fite BioPharma Ltd., an Israeli clinical-stage biopharmaceutical company, specializes in the creation of small molecule therapeutic prod…$2.1M——−27.7%−80.7%
567BioRestorative Therapies, Inc.BRTXBioRestorative Therapies, Inc.$2.1M——−8.5%−94.6%
56860 Degrees Pharmaceuticals, Inc.SXTP60 Degrees Pharmaceuticals, Inc.$2.1M——+68.0%−88.6%
569Co-Diagnostics, Inc.CODXCo-Diagnostics, Inc.$1.9M——−28.1%−97.8%
570Propanc Biopharma, Inc.PPCBPropanc Biopharma, Inc.$1.8M———−99.4%
571Calidi Biotherapeutics, Inc.CLDICalidi Biotherapeutics, Inc.$1.8M———−97.4%
572Curis, Inc.CRISCuris, Inc., a biotechnology company, engages in the discovery and development of drug candidates for the treatment of human cancers in the…$1.8M——−62.2%−96.9%
573XORTX Therapeutics Inc.XRTXXORTX Therapeutics Inc.$1.7M———−68.7%
574Kairos Pharma, Ltd.KAPAKairos Pharma, Ltd.$1.7M———−92.0%
575Creative Medical Technology Holdings, Inc.CELZCreative Medical Technology Holdings, Inc., a biotechnology firm based in Phoenix, Arizona, specializes in advancing adult stem cell treatme…$1.6M——−50.0%−79.1%
576GeoVax Labs, Inc.GOVXGeoVax Labs, Inc.$1.6M———−98.8%
577Oragenics, Inc.OGENOragenics, Inc.$1.6M———−68.8%
578TransCode Therapeutics, Inc.RNAZTransCode Therapeutics, Inc.$1.5M———−84.3%
579Silo Pharma, Inc.SILOSilo Pharma Inc.$1.5M——−25.0%−82.0%
580XTL Biopharmaceuticals Ltd.XTLBXTL Biopharmaceuticals Ltd.$1.5M———−61.3%
581PMGC Holdings Inc.ELABPMGC Holdings Inc.$1.3M———−100.0%
582Karyopharm Therapeutics Inc.KPTIKaryopharm Therapeutics Inc.$1.2M——+6.8%−98.9%
583Radiopharm Theranostics LimitedRADXRadiopharm Theranostics Limited, an Australian company established in Carlton in 2021, specializes in the research and development of cuttin…$1.2M———−78.8%
584NewcelX Ltd.NCELNewcelX Ltd., a biotechnology firm established in 2008 and based in Zurich, Switzerland, is dedicated to advancing groundbreaking therapeuti…$1.2M8.3x——−34.4%
585Bone Biologics CorporationBBLGBone Biologics Corporation, a medical device enterprise, specializes in fostering bone regeneration for spinal fusion, leveraging its advanc…$1.1M———−82.5%
586Valion Bio, Inc.VBIOValion Bio, Inc.$1.1M——−139.8%−99.1%
587Virax Biolabs Group LimitedVRAXVirax Biolabs Group Limited is a biotechnology company focused on the detection of immune responses to and diagnosis of viral diseases.$1.1M——−87.7%−93.7%
588Genprex, Inc.GNPXGenprex, Inc.$1M———−98.0%
589Jaguar Health, Inc.JAGXJaguar Health, Inc., a commercial-stage pharmaceutical firm, specializes in developing prescription therapies for both human and animal pati…$939K——+135.5%−100.0%
590Lunai Bioworks Inc.LNAILunai Bioworks Inc.$830K———−97.9%
591Lakewood-Amedex Biotherapeutics, Inc.LABTLakewood-Amedex Biotherapeutics, Inc.$676K———−99.3%
592Moolec Science S.A.MLECMoolec Science SA, a science-based ingredient company, engages in the development of ingredients for food, pet food, animal feed, and dietar…$617K———−91.2%
593CDT Equity Inc.CDTCDT Equity Inc., a data-driven biopharmaceutical company, focuses on identifying, enhancing, and monetising therapeutic assets.$611K———−100.0%
594Decoy Therapeutics Inc.DCOYBased in Cambridge, Massachusetts, Decoy Therapeutics Inc.$601K———−96.7%
595Matinas BioPharma Holdings, Inc.MTNBMatinas BioPharma Holdings, Inc.$508K———−93.5%
596SeaStar Medical Holding CorporationICUCWBased in Denver, Colorado, SeaStar Medical Holding Corporation operates as a medical device company.$440K——+123.6%−61.8%
597Tessera Defense and Homeland Security IncHLSQTessera Defense & Homeland Security, Inc.$362K———−81.8%
598HCW Biologics Inc.HCWBHCW Biologics Inc.$355K——+707.0%−94.9%
599SciSparc Ltd.SPRCSciSparc Ltd.$243K——−68.3%−98.3%
600Biodexa Pharmaceuticals PlcBDRXBiodexa Pharmaceuticals Plc, a biopharmaceutical company in the clinical development stage, is dedicated to advancing a diverse portfolio of…$231K———−98.8%
601Scinai Immunotherapeutics Ltd.SCNIScinai Immunotherapeutics Ltd.$228K——+10.9%−95.8%
602Purple Biotech Ltd.PPBTPurple Biotech Ltd., a clinical-stage biotechnology firm based in Rehovot, Israel, is dedicated to pioneering treatments that help cancer pa…$181K———−82.3%
603Niki BioSolutions, Inc.NIKINiki BioSolutions is a biopharmaceutical company that resulted from the merger of Aptorum Group and DiamiR Biosciences.$129K———−98.8%
604Silexion Therapeutics Ltd.SLXNSilexion Therapeutics LTD is a biopharmaceutical company specializing in the discovery and advancement of RNA interference (RNAi)-based canc…$61K———−99.5%
605Psyence Biomedical Ltd.PBMPsyence Biomedical Ltd.$56K———−80.3%
606CDT Equity Inc.CDTTWCDT Equity Inc., established in October 2021 by David Joszef Tapolczay and Freda C.$8K———−60.6%

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